RESONACE - Haloperidol 0.25mg. Tabs.

Composition Each tablet contains: Haloperidol 0.25mg. Product Description Haloperidol is a conventional, or typical, butyrophenone antipsychotic drug Mechanism of Action Haloperidol is a neuroleptic and a butyrophenone. Due to its strong central antidopaminergic action, it is classified as a highly potent neuroleptic. It is approximately 50 times more potent than chlorpromazine on a weight basis (50mg chlorpromazine are equivalent to 1mg haloperidol). Pharmaco Kinetics Bioavailability - Approx. 60 to 70% (tablets and liquid) ; Metabolism hepatic ; Half life 12 to 36 hours ; Excretion Biliary and renal. Indications Chronic schizophrenia, mania, behavioural disturbances, refractory agitation.

Dosage Parenteral medication, administered intramuscularly in doses of 2 to 5 mg, is utilized for prompt control of the acutely agitated schizophrenic patient with moderately severe to very severe symptoms. Depending on the response of the patient, subsequent doses may be given, administered as often as every hour, although 4 to 8 hour intervals may be satisfactory. Contra Indication Special Precautions Predispositive factors may be female gender, prexisting affective disorder and cerebral dysfunction.. Drug Interactions Adverse Effects The drug is noted for its strong early and late extrapyramidal side-effects. The risk of tardive dyskinesia is around 4% per year in younger patients, higher than with most other antipsychotic drugs. In patients over the age of 45, the percentage of those afflicted can be even higher. Packing A strip of 10 tablets.